Synthesis and characterization of CuO nanoparticles stabilized by quercetin and its application for anti-breast cancer activity

The main idea in this research used quercetin (QT) as a stabilizing agent to prepare CuO nanoparticle (NPs). QT is pigment which exists from plants, fruits, and some medicines. It contains numerous hydroxyl groups, works complexing self-assembly agent. prepared CuO-NPs were characterized by fourier transformed infrared (FT-IR), X-ray diffraction (XRD), scanning transmission electron microscopy (SEM TEM), energy-dispersive analysis (EDX). structure investigation confirm that the polycrystalline nature having monoclinic crystalline form showed (111) preferential orientations. estimated particle sizes XRD, TEM, SEM ranged 12.03 15.3 nm. Surface displayed homogeneously distributed with spherical shape. On other hand, synthesized tested for anticancer activity on human Breast. infected cell (MCF-7) uses MTT (3-(4,5-dimethyl-2-triazolyl)-2,5-diphenyl-2-tetrazolium bromide) test. inferred clarify high cytotoxicity of an IC50 μM value 57.6 42.8 µg/mL 24 72 h respectively.